Metaphase Spindles Rotate in the Neuroepithelium of Rat Cerebral Cortex

Metaphase spindles rotate in the neuroepithelium of rat cerebral cortex.

Time-lapse confocal microscopy has been used to image cells in mitosis at the apical surface of neuroepithelium from the rat cerebral cortex during the period of neurogenesis. Staining with vital chromatin dyes reveals that mitotic spindles that are aligned parallel to the surface of the tissue are highly motile, rotating within the plane of the epithelium throughout metaphase, and come to rest...

Effect of paraoxon on the synaptosomal GABA uptake in rat hippocampus and cerebral cortex

Introduction: Paraoxon (the neurotoxic metabolite of organophosphorus (OP) insecticide, parathion) exerts acute toxicity by inhibition of acetylcholinesterase (AChE), leading to the accumulation of acetylcholine in cholinergic synapses and hence overstimulation of the cholinergic system. Since, reports on changes in the level of γ- amino butyric acid (GABA) during OP-induced convulsion have bee...

Evaluation the protective effect of aminoguanidine on cortex and striatum damage in acute phase of focal cerebral ischemia in rat

Introduction: Several studies have indicated that late treatment of aminoguanidine (AG) reduces cerebral ischemic injuries in animal models. However, the effects of early treatment of AG on cerebral ischemic damage are not well understood. This study was designed to evaluate effect of early treatment of AG on cortex and striatum injuries as well as neurological dysfunctions in transient mode...

donepezile prevents morphine-induced apoptosis in rat cerebral cortex

Spatiotemporal Profiles of Proprioception Processed by the Masseter Muscle Spindles in Rat Cerebral Cortex: An Optical Imaging Study

Muscle spindles in the jaw-closing muscles, which are innervated by trigeminal mesencephalic neurons (MesV neurons), control the strength of occlusion and the position of the mandible. The mechanisms underlying cortical processing of proprioceptive information are critical to understanding how sensory information from the masticatory muscles regulates orofacial motor function. However, these me...